I enjoyed my managers (before they were fired) and the majority of my co-workers were pleasant as well. My daily duties at Helix weren't too demanding, and I was paid adequately for the tasks that I completed. Only accept a job here if you are desperate. I would highly recommend that you avoid this business if you already have a job, do not let them poach you. If the drug causes a serious side effect … that is a potential tragedy.Helix wasn't necessarily a bad place to work -until it was. " Prescribing a drug that does not work for the patient is a serious problem. Identifies if current medication(s) are appropriate treatment options or if a modification may be warrantedĬurrent panels include: psychiatry, cardiac, pain and comprehensive panels Provides safer medications and doses tailored for each unique patient’s need Improves patient compliance to a medication and treatment plan Painless testing uses a cheek swab application instead of needlesĭelivers straightforward, transparent results to physicians with easy-to-read reports Maximizes drug dose response for more effective medical care Minimizes side effects for safer treatment plans Identifies possible drug-to-drug interactions by using the most advanced technology available
Reduces potential adverse drug side-effects The benefits of pharmacogenomics PGx testing include:ĭetermines best fit for individual patient medication(s) This is a cash pay test only and is not covered by insurance at Helix Diagnostics at this time. Once the sample is received at the lab, results will be available in 14 days. To obtain a sample requires only a simple cheek swab. Helix Diagnostics therefore offers a mental health profile, cardiac profile, pain profile and comprehensive profile.
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Reviewing a patient's genetic profile allows a more personalized approach to medicine and eliminates trial and error for more effective, quicker and safer therapies. When we combine the pharmacokinetic and pharmacodynamic profiles, we get a precision list of medications that can be used for the patient, based on their individual metabolism and biological processes. Focusing on the correct medication with the first prescription saves both the patient and the medical provider time, money, and from potential adverse outcomes. On average, 38 percent of patients with depression show no response to initial treatments. Extensive research has been performed for many mental health and cardiac medications, as well as pain and neurologic medications. Genetic variations may impact a drug’s effect by altering its pharmacokinetics, pharmacodynamics, or both. Drug transport throughout the body is affected by these genes and drug response can be determined by assessing for variants of these pharmacodynamic factors. Pharmacodynamic testing looks at how well the target receptors, ion channels, transporter proteins and enzymes respond to a given drug. Regarding pharmacodynamics, think of this as what a drug does to the body. Conversely, it can also lead to an elevated level of medications in the patient that may cause harm and adverse effects. These enzymes play an important role in metabolism in up to 70 percent of medications.Ī variant in one of these enzymes can lead to an absence of therapeutic threshold (the amount of drug needed in the body) for treatment. Accordingly, pharmacokinetic testing looks at how fast or slow enzymes metabolize drugs through assessing variants of these enzymes, such as cytochrome P450 enzymes. Think of pharmacokinetics as what our body does to a drug. It helps to first understand that pharmacogenomics includes two assessments, pharmacokinetics and pharmacodynamics. Knowing this, Helix Diagnostics hopes to offer greater testing options in this growing sector of pharmacology. And since 75 percent of patients have at least one significant genetic variant, atypical drug metabolism is the result. Variants of genes in an individual’s genetics leads to variability of drug responses. Pharmacogenomics, also sometimes called pharmacogenetics, is the study of how our genes alter our response to medications. MAKING PRECISION MEDICINE POSSIBLE WITH PHARMACOGENOMICS
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